Scintigraphic detection of tumour necrosis factor in patients with rheumatoid arthritis
نویسندگان
چکیده
منابع مشابه
Scintigraphic detection of tumour necrosis factor in patients with rheumatoid arthritis.
OBJECTIVES To investigate the biodistribution and specific targeting for tumour necrosis factor (TNF) of a fully human, radiolabelled anti-TNF monoclonal antibody (anti-TNF mAb) in patients with active rheumatoid arthritis (RA). To assess whether this agent is suitable for visualisation of synovitis. METHODS Ten patients with RA underwent whole body scintigraphy after administration of a trac...
متن کاملTumour necrosis factor in serum and synovial fluid of patients with active and severe rheumatoid arthritis.
Fifteen serum samples and 29 synovial fluids of patients with rheumatoid arthritis (RA) were examined for the presence of tumour necrosis factor (TNF). The assay for TNF was based on the cytotoxic activity of this cytokine for human melanoma cells in tissue culture. High concentrations of TNF were found in serum samples of patients with severe RA, who had increased erythrocyte sedimentation rat...
متن کاملCutaneous manifestations in patients with rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with different extra-articular manifestations. Among those extra-articular manifestations, there are significant cutaneous manifestations which may result in first admission to a dermatologist. In this article some specific and non-specific skin lesions of RA such as rheumatoid nodules, exacerbated nodules, rheumatoid vascu...
متن کاملHearing status in patients with rheumatoid arthritis
Background: Previous studies showed that one of the complications of rheumatoid arthritis disease was auditory disorder. The goal of the present study was to compare the auditory status in patients with rheumatoid arthritis and healthy individuals. Methods: In the present case-control study, 30 normal persons and 60 persons with rheumatoid arthritis with mean age of 46.72 and standard deviatio...
متن کاملWhen patients with rheumatoid arthritis fail tumour necrosis factor inhibitors: what is the next step?
The advent of biological agents in general and tumour necrosis factor (TNF) inhibitors in particular has dramatically changed the outcomes and outlooks for patients with rheumatoid arthritis (RA). Not only have they expanded the treatment options in quantitative terms, but their combination with methotrexate (MTX) or other disease-modifying antirheumatic drugs (DMARDs) has also led to a quantit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2003
ISSN: 0003-4967
DOI: 10.1136/ard.62.9.825